ChemicalBook > CAS DataBase List > 2'-O-MOE-5MeU-3'-phosphoramidite
2'-O-MOE-5MeU-3'-phosphoramidite
- Product Name
- 2'-O-MOE-5MeU-3'-phosphoramidite
- CAS No.
- 163878-63-5
- Chemical Name
- 2'-O-MOE-5MeU-3'-phosphoramidite
- Synonyms
- 5-Me-DMT-2'-O-Me-Ur;5'-O-DMT-2'-O-MOE-T-CE;5-Me-DMT-2'-O-MOE-U-CE;2'-MOE Thymidine Amidite;2'-MOE-U CE Phosphoramidite;5-Methyl-2 '- Methoxyuridine;2'-O-MOE-T-CE Phosphoramidite;2'-O-MOE-5-Me-U Phosphoramidite;2’-O-MOE-5MeU-3’-phosphoramidit;2'-O-MOE-5MeU-3'-phosphoramidite
- CBNumber
- CB62459682
- Molecular Formula
- C43H55N4O10P
- Formula Weight
- 818.89
- MOL File
- 163878-63-5.mol
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2'-O-MOE-5MeU-3'-phosphoramidite Property
- pka
- 9.55±0.10(Predicted)
- InChI
- InChI=1/C43H55N4O10P/c1-29(2)47(30(3)4)58(55-24-12-23-44)57-38-37(56-41(39(38)53-26-25-50-6)46-27-31(5)40(48)45-42(46)49)28-54-43(32-13-10-9-11-14-32,33-15-19-35(51-7)20-16-33)34-17-21-36(52-8)22-18-34/h9-11,13-22,27,29-30,37-39,41H,12,24-26,28H2,1-8H3,(H,45,48,49)/t37-,38-,39-,41-,58?/s3
- InChIKey
- YFRRKZDUDXHJNC-UHDLEJOUNA-N
- SMILES
- O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,37,43,r|
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
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2'-O-MOE-5MeU-3'-phosphoramidite Chemical Properties,Usage,Production
Chemical Properties
white to off-white powder
Uses
5''-O-DMT-2''-O-methyl-5-methyluridine is a uridine-derived oligonucleoside (U829910) used in the synthetic preparation of nucleic acids.
General Description
2'-O-MOE-5MeU-3'-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
General Description
Like the very similar 2’-OMe backbone, the 2’-O-methoxyethyl-RNA (2’-MOE) backbone provides enhanced duplex stability, significant nuclease resistance and relatively low toxicity. As a result, 2’-MOE has been an attractive backbone for many therapeutic candidates, several of which have been approved by the FDA. These drugs have included 1) 2’-MOE/DNA chimeras to facilitate RNase H cleavage of target RNA sequences as well as 2) steric blocking oligonucleotides to alter the splicing of mRNA. The standard 2’-MOE nucleotides are A, 5-Me-C, G and 5-Me-U.
2'-O-MOE-5MeU-3'-phosphoramidite Preparation Products And Raw materials
Raw materials
Preparation Products
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2'-O-MOE-5MeU-3'-phosphoramidite Suppliers
- Tel
- 16314854226
- Fax
- 1-631-614-7828
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 9713
- Advantage
- 58
- Tel
- +1-631-485-4226
- Fax
- 1-631-614-7828
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 19553
- Advantage
- 58
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View Lastest Price from 2'-O-MOE-5MeU-3'-phosphoramidite manufacturers
SHANGHAI NOVRIBO BIOTECH
- Product
- 2'-MOE-U CE Phosphoramidite 163878-63-5
- Price
- US $100.00/kg
- Min. Order
- 0.009999999776482582kg
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2023-03-20
Hefei Huana Biomedical Technology Co.,Ltd.
- Product
- 5'-O-DMT-2'-O-MOE-T-CE 163878-63-5
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- ≥98%
- Supply Ability
- 20tons
- Release date
- 2023-03-09
Henan Aochuang Chemical Co.,Ltd.
- Product
- 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite 163878-63-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-26
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